First Professional MBBS exam subjects:

  • Anatomy & Histology
  • Physiology
  • Biochemistry
  • Islamiyat & Pakistan Studies

Subject: Physiology

Total number of lectures= 144
Tentative date of course completion: October 31, 2021

UnitTotal lecturesTutor name
Cell Physiology12Dr. Mudassar Roomi, Dr. Huma
Blood Physiology22Dr. Shagufta, Dr. Mudassar Roomi, Dr. Huma
Nerve and Muscle Physiology25Dr. Mudassar Roomi, Dr. Huma
Heart Physiology22Dr. Mudassar Roomi, Dr. Shagufta
Circulation Physiology30Dr. Shagufta, Dr. Mudassar Roomi, Dr. Huma
Respiration Physiology25Dr. Shagufta, Dr. Mudassar Roomi
Deep sea & high altitude physiology4Dr. Huma, Dr. Shagufta
Skin & temperature regulation4Dr. Huma, Dr. Shagufta

Subject: Anatomy & Histology

Course duration=====36 weeks (working)

Total number of lectures= 272 (8 lectures/week)
Tentative date of course commencement:
Tentative date of course completion:

UnitTotal lectures
Tutor name
General Embryology+ special
56Prof. Dr. Mamoona Naheed
General Histology55Prof. Dr. Irfan Qadir
General Anatomy25Dr. Sadia
Gross anatomy A. Upper Limb25+25Prof. Mian Azhar & Dr. Sadia
Gross anatomy B. Lower Limb25+25Prof. Mian Azhar &Dr. Sadia
Gross anatomyC. Thorax18+18Prof. Mian Azhar& Dr. Sadia

Subject: Biochemistry

Total number of lectures= 100
Tentative date of course completion: October 31, 2021

Unit Total lecturesTutor name
Cell Biochemistry10Dr.Shamim,Dr.Saleem
Ph, Buffer8Dr.Talmeez
CHO Chemistry8Dr.Saleem
Amino acids & Proteins15Dr. Talmeez, Dr.Saleem
Lipids Chemistry12Dr.Shamim
Nucleic acids6Dr.Shamim
Enzymes8Dr.Shamim , Dr.Saleem
Heme Metabolism8Dr.Saleem
Vitamins15Dr.Saleem, Dr.Shamim
Extra cellular matrix4Dr. Talmeez

  Gen. AnatomyGen. HistologyGen. EmbryologyGross Anatomy 
WEEK 1Introduction to Physiology, Homeostasis, Composition of blood1.Introduction to anatomy,   2.General anatomy TerminologyIntroduction of microscopeGametogenesis: Cell division    1.Clavicle 2.ScapulaI 3.ScapulaII 4.Pectoral Region 1Orientation week Faculty , Biochemistry ,Syllabus ,Assessment, TOS.
WEEK 2Cell organelles, RBCs: erythropoiesis1.Bone: classification   2.Bone: parts of long boneCell organelles iChromosomal abnormalities1.Pectoral Region II 2.Mammary gland 3.Sternoclavicular Joint I 4.Sternoclavicaular Joint IICell introduction, Cell organelles,  Cell membranes and their chemical composition
WEEK 3Functional systems of cell, Cell adhesions, cell modifications, RBCs: Anemias & polycythemias1.Bone: ossification   2.Bone: blood supply and clinicals Cell organelles iiGametogenesis: Oogenesis1.AxillaI (Boundaries, contents) 2.AxillaII (Axillary vessels) 3.Axillary lymph nodes 4.Axillary sheath and clinicalsImportance of lipids and proteins in cell membranes Membrane transport including active transport, passive transport.  
WEEK 4Genetics, WBCs: leukopoiesis, WBCs: functions, inflammation1.Structural &functional classification of joints   2.Characteristics & movements of synovial joints    Cell membrane i  Spermatogenesis   Clinical Correlates1.Brachial Plexus 2. Injuries of Brachial plexus 3. Back I: Fascia, muscles 4. Back II, intermuscular spaces. Receptor, G Protein & Signal transduction. Methods to study cell biochemistry (microscopy, centrifugation,      spectrophotometry, chromatography, electrophoresis and thermal cycler
WEEK 5Membrane transport, Reticuloendothelial system, Abnormalities of WBCs1.Dislocation and injury of joints   2.Classification of musclesCell membrane iiFirst week of development Ovarian cycle and ovulation  1.Humerus I 2.Humerus II 3.Shoulder Joint 4.Rotator Cuff  Ionization of water, week acids and bases, pH and pH scale pK values, dissociation constant and titration curve of weak acids
WEEK 6Apoptosis vs necrosis, cancer Immunity: classification, antibodies, complement system1.Parts of a muscle   2.Blood & nerve supply of muscle The cytoskeletonFertilization with clinicals1.Arm I a. Ant. compartment 2. Arm II b. Ant. compartment 3.Arm II a. Post .comp 4.ArmII b. Post. Comp  Body buffers and their mechanism of action Henderson – Hasselbach‟s equation Acid base regulation in human body Biochemical mechanisms for control of water and electrolyte Balance
WEEK 7Resting potential, Autoimmune diseases, allergy1.Anatomy of neuromuscular junction   2.Sprain spasm and injury of muscleCell nucleusContraception and infertility1.Radius 2.Ulna I 3.Ulna II 4.Elbow Joint  Carbohydrates definition, their biochemical function and classification. Structure and functions of monosaccharides and their derivatives

WEEK 8Action potential, Blood groups, blood transfusion reactions, Rh incompatibility1.CVS i   2.CVS iiCell cycleCleavage and blastocyst formation Clinicals1.Cubital Fossa Forearm I a. Ant. comp 2.Forearm I b. Ant .comp    3.ForearmII a. Post. comp 4.ForearmII b. Post. compDisaccharides and their important examples Oligosaccharides and their combination with other macromolecules  
WEEK 9Synapses, nerve fiber classification, Hemostasis: stages, platelets, intrinsic & extrinsic pathways1.Lymphatic system i   2.Lymphatic system ii    Epithelium iImplantation & Clinicals1.Hand; Bones, wrist joint 2.Palm I 3.Palm II 4.Palm IIIPolysaccharides and their biochemical role-Homopolysacharides, Heteropolysacharides-GAG’S, Glycoconjugates(proteoglycans/Glycoproteins Mucopolysacaridosis.    
WEEK 10Neuromuscular junction, myasthenia gravis, Clotting and bleeding disorders1.Nervous system i   2.Nervous system iiEpithelium iiSecond week of development Bilaminar germ disc  1.Dorsum of hand 2. Veins of UL 3. Lymphatic drainage 4. Dermatomes and innervationClassification of Aminoacids: standard/Non-standard Essential/Non-Essential, Classification of Proteins-Structural, Classification of Proteins-Functional
WEEK 11Skeletal muscle : mechanism of contraction, excitation-contraction coupling, Properties of caridac muscle1.Skin     2.FasciaConnective tissue: cells, fibers & typesThird week of development Gastrulation1.Surface marking 2. Radiology 3. Spotting 4. RevisionThree dimensional structures of Proteins. Primary, secondary, Tertiary & quaternary, Haemoglobin structure, Haemoglobinopathies.
WEEK 12Term test 1   TERM EXAM !
 Gen. HistologyGen. EmbryologyGross Anatomy 
WEEK 13Smooth muscle: mechanism of contraction, excitation-contraction coupling, Electrical activities in the heart1.Muscle i   2.Muscle ii  1.Notochord Formation Clinicals   2.Embryonic Period 3-8 week Derivatives of ectoderm Neurulation1.Hip bone I 2.Hip bone II 3.Hip bone III 4. Thigh I a. Ant. comp.  Types of Collagen ,structure , biosynthesis,degradation of collagen,Collagenopathies(Scurvey,Marfansyndrome,osteogenesis imperfect ),abnormal intracellular deposits of proteins Immunoglobulins structure and functions.
WEEK 14Hemodynamics of circulation, Cardiac conduction system, Effects of ANS on heart1.Circulatory system: capillaries   2.Circulatory system: arteries  1.Differentiation of mesoderm   2.Derivatives of mesoderm1.Thigh I b. Ant. comp 2.Thigh II a. Med. comp 3.Thigh III b. Med. comp 4.ClinicalsPlasma proteins, Protein separation techniques (Electrophoresis/Isoelectrc  Focusing/Chromatography
WEEK 15Blood flow regulation, pulses, Caridac cycle and its phases1.Circulatory system: veins& lymphatics   2.Heart  1.Derivatives of Endoderm   2.Clinicals of germ layer derivatives1.FemurI 2.FemurII 3.Gluteal Region I 4.Gluteal Region IINucleotides and their biochemical role. . Structure, function and biochemical role of nucleotides,  derivatives of purines and pyramidines and their clinical role

WEEK 16Resistance, regulation of venous return, Normal ECG, cardiac vectors1.Unilocular adipose tissue   2.Multilocular adipose tissue  1.Folding of embryo Clinicals   2.Early dev. of CVS1.Hip Joint I 2.Hip Joint II 3.ThighIII a. Post. comp 4.ThighIII b. Post. compStructure, function and types of nucleic acids,DNA & RNA
WEEK 17Lymphatic system, microcirculation and edema, Arrhythmias: normotropic1.Cartilage i, 2.Cartilage ii  1.Formation of body cavities   2.Clinicals1.Tibia 2.Fibula I 3.Fibula II 4. Knee Joint IClassification of lipids and their biochemical functions, Structure and biochemical function of phospholipids, glycolpids, andsphingolipids, Classification of fatty acids and their biochemical functions
WEEK 18Cardiac output and its regulation, Arrhythmias: ectopic1.Bone: cells 2.Bone: matrix  1.Third Month to birth Monthly changes in the development of fetus   2.Clinicals1.Knee Joint II 2. Leg I a. Ant. And lat. comp 3.Leg II Post. comp 4.Popliteal Fossa and contentsFunctions of essential fatty acids, Eicosanoides and their function in health and disease, Steroids and their biochemical role, Cholesterol, its structure chemistry and function
WEEK 19Short term regulation of blood pressure, Mechanics of ventilation1.Types of bone   2.Histogenesis of Bone  1.Fetal membranes and placenta Structure of placenta 2.Placental circulation, Functions of placenta Clinicals1.Tibiofibular Joints 2. Articulated Foot 3.Bones of Foot 3.Ankle joint I 4. Ankle Joint IILipid peroxidation and its significance, Lipoprotein Structure, Fatty Liver
WEEK 20Long term regulation of blood pressure, surfactant, compliance, dead space1.Bone growth & remodeling   2.Metabolic role of bone tissue & joints  1.Umbilical Cord and cord abnormalities   2.Amniotic Fluid with clinicals1.Dorsum of Foot I 2. Dorsum of Foot II 3. Clinicals 4.Sole IEnzyme-Nomenclature, Classification of Enzymes, Properties of Enzymes, Enzymes and catalysts
WEEK 21Hypertension, coronary blood flow, MI, Lungs function tests1.Nervous system: neuron   2.Nervous system: cerebral cortex  1.Twin pregnancy   2.Clinicals1.Sole II 2.Sole III 3.SoleIV 4. Clinicals  Co-enzymes and co-factors, Iso-enzymes and their clinical importance, Factors affecting enzyme activity (Michaelis – Menten and Lineweaverbuk, Regulation of enzyme Activity
WEEK 22Cardiac failure, Pulmonary circulation & edema1.Nervous system: cerebellar cortex   2.Spinal cord    1.Birth defects; Types of abnormalities   2.Principals of teratology  1.Veins of lower limb 2.Lymphatic Drainage 3. Dermatomes and cut. innervation 4. RevisionClassification of enzyme inhibitors and their biochemical importance, Therapeutic use and application of enzymes in clinical diagnosis, Enzyme Deficiency Diseases.
WEEK 23Circulatory shocks, Physical principals of gas exchange1.Nervous system: Peripheral nerve & Ganglia   2. Tutorial    1.Teratogens associated with human malformation   2.Clinicals1.Surface Marking 2.Radiology 3. Spotting 4.RevisionSynthesis and structure of haemoglobin, Types and function of haemoglobin, O2 binding capacity of haemoglobin and factors regulating & affecting it
WEEK 24Term test 2                                  TERM EXAM 2
WEEK 25Regional circulations: cerebral, fetal, V/Q ratio1.Immune system 2.Lymphoid organs -Thymus  1.Prenatal diagnosis   2.Fetal Therapy1.Thoracic apertures 2.Skeleton of Thorax´-vertebrae 3. Sternum 4.Ribs IBreakdown of haemoglobin, formation of bile pigments their transport and
excretion, Biochemical causes of hyper-bilirubinaemia and differentiation between
different types of jaundice.
WEEK 26Regional circulations: skin, CVS changes during exercise, Transport of gases in blood1.Lymphoid organs -spleen i   2.Lymphoid organs -spleen ii1.Skeletal system I 2.Clinicals1.Ribs II 2.Joints of thoracic wall 3.Movements of thoracic wall 4.Muscles of thoracic wallClassification of Porphyrias,  review of haemoglobinopathies
WEEK 27High altitude physiology,  Nervous regulation of respitaion1.Lymphoid organs -Lymph node   2.Lymphoid organs -Tonsil1.Skeletal system II 2. Clinicals1.Neurovasculature of thoracic wall I 2. NV of Thoracic wall II 3.DiaphragmI 4.DiaphragmIIClassification of vitamins, their chemical structure & biochemical function, Daily requirements, sources, functions and deficiency effects  of fat soluble vitamins-Vitamin A & D
WEEK 28Deep sea physiology, Chemical regulation of respitaion1.Respiratory system -Trachea   2. Epiglottis1.Muscular system I   2. Clinicals1. Mediastinum I 2. Mediastinum II 3. Mediastinum III 4.MediastinumIVVitamin E and Vitamin K, Water soluble Vitamins-Vitamin C & B1(Thiamine)
WEEK 29Pathophysiology of respiratory diseases: asthma, emphysemaRespiratory system -Lungs1.Muscular system II   2. Clinicals1.Pleura I 2.Pleura II 3.Pleura III 4.Lungs IVitamin B2(Riboflavin),B3(Niacin, Pantothenic acid and Biotin.
WEEK 30Pathophysiology of respiratory diseases: cyanosis, hypoxia, restrictive lung diseases1.Integumentary system- thick skin   2.Thin skin & hair follicle1.Limb I   2. Clinicals  1.Lungs II 2.Lungs III 3.Lungs IV 4.Pericardium IFolic acid and Cobalamin(B12), Role of vitamins as co-enzymes, Hypervitaminosis
WEEK 31Skin and temperature regulation,  Pathophysiology of respiratory diseases: restrictive lung diseasesMammary gland & its phases1.Limb II   2.Clinicals1.Pericardium II 2.Heart I 3.Heart II 4.Heart IIIMinerals in human nutrition, sources, biochemical actions and recommended daily allowance (RDA) Sodium ,potassium & Calcium and Phosphorus
WEEK 32Abnormalities of temperature regulation: fever, heat stroke, hypothermiaRevisionRevision1.Heart IV 2.Surface Marking 3.Surface Marking I 4.Surface Marking IIIron metabolism, Zinc & Copper ,Selinium. iodine Sulphur, magnesium, flouride
WEEK 33Revision weekRevisionRevisionRadiologyCaloric requirements of the body. Balanced diet
Protein energy malnutrition, Marasmus & Kwashiorkor
WEEK 34Revision weekRevisionRevisionSpottingNutritional requirements in Pregnancy & Lactation. Types of Collagen ,structure , biosynthesis,degradation of collagen, Collagenopathies,
WEEK 35Revision weekRevisionRevisionSpotting ELASTIN ,Characteristics of Elastin, Role. Glycoaminoglycans structure, Classification ,functions & disorders.
WEEK 36Revision weekRevisionRevisionRevision Revision