Name of HOD: Prof Dr. Muhammad Zahid Qamar
To provide quality education in the field of pharmacology & therapeutic at par with international standards.
The mission of pharmacology department is contribute towards that is to prepare the competent inspiring and empathetic health professionals and researchers who can contribute cost-effective health care to community and are ready to adapt the changes along with effective collaboration with in interdisciplinary teams.
Undergraduate teaching program in Pharmacology & Therapeutics is providing students with knowledge of scientific basis of its application using interactive teaching strategies. In a systematic manner our department wants to facilitate students to understand subject with clinical significance involving the study of dynamics, kinetics, therapeutics, adverse effect, contraindications and possible drug interactions, experimental pharmacology and pharmacy.
The Department of Pharmacology and Therapeutics is providing holistic, integrated medical education to MBBS, BDS and allied health students. As a pre- clinical science unit of Kishwar Fazal teaching hospital, it makes an integral link between Basic Medical & Clinical Sciences. The outcomes of the department are
- To provides 3rd year MBBS & BDS students solid understanding of basic Pharmacology & Therapeutics
- To strengthen medical education in relation to pharmacology for health professionals including faculty members, students of MBBS, BDS, and Allied health professionals for effective, safe and ethical use of medicine in the community.
- To prepare MBBS students and students of allied health sciences like DPT with up-to-date knowledge of the subject.
- To prepare students for life time learning and problem solving skills through clinical presentation, assignments and small group discussions.
- To provide research facility in basic and clinical pharmacology
- HOD’s office
- Professor’s office
- Assistant professor’s office
- Demonstrator’s office
- Pharmacology laboratory
- Pharmacology museum
- Small group discussion rooms
The details of the syllabus are as under:
- General Pharmacology:
- Definition of Pharmacology, Objectives of learning Pharmacology, definition of drug and drug nomenclature.
- Standard sources of drug information, pharmacopoeias, and formularies.
- Branches/Divisions of Pharmacology.
- Sources of drugs.
- Active principles of drugs and Pharmacopoeias.
- Dosage forms and doses of drugs.
- Drug administration.
- Absorption of drugs and processes involved in drug absorption ( transport of drugs across cell-membrane)
- Factors modifying absorption of drugs.
- Bioavailability, its clinical significance and factors affecting bioavailability.
- Drugs reservoirs, distribution and redistribution of drugs, plasma protein binding.
- Pro-drug, Biotransformation of drugs, enzyme induction, enzyme inhibition and entero-hepatic circulation.
- Plasma half-life of drugs, steady state concentration, its clinical importance and factors affecting it.
- Excretion of drugs.
- Mechanism of drug action.
- Dose response curves, structure-activity relationship.
- Factors modifying action and doses of drugs.
- Drug-drug interactions.
- Locally Acting Drugs
- Demulcents, Emollients, Irritants, Counter irritants, Astringents, anti-seborrhoeics, Locally acting enzymes.
- Antiseptics and Disinfectants
- Drugs Acting on Gastrointestinal Tract
- Anti Emetics
- Drugs affecting motility of GIT
- Ulcer Healing drugs
- Cardiovascular Drugs
- Anti-arrhythmic Drugs
- Inotropic Drugs/Drugs used in cardiac failure.
- Anti-hypertensive Drugs
- Anti-anginal Drugs
- Anti-hyperlipidemic Drugs
- Drugs Acting on Autonomic Nervous System
- Choline Esters.
- Cholinomimetic Alkaloids
- Alpha Adrenergic receptor Blockers.
- Beta Adrenergic receptor Blockers
Adrenergic Neurone Blockers
Autonomic Ganglionic Blockers
Skeletal Muscle Relaxants
- a) Neuromuscular Blocking Agents.
- b) Central Muscle Relaxants.
- c) Directly acting skeletal muscle and relaxants.
- Central Nervous System 3
- General Anaesthetics
- Local Anaesthetics
- Drugs for Movement Disorders/ Anti Parkinsonism Drugs
- Drugs for Migraine
- a) Opioids
- b) Non-Steroidal Anti-Inflamatory Drugs (NSAID)
- c) Anti-gout Drugs
- d) DMARDs
- Drugs Acting on Respiratory System
- Drugs used in treatment of Bronchial Asthma
- Drugs Acting on Endocrine System:
- Pituitary-Hypothalamic Drugs
- Sex Hormones/Hormonal contraception
- Thyroid/ Parathyroid Drugs
- Pancreatic Hormones and Oral Antidiabetic Agents
- Drugs used in infertility
Drugs Acting on Uterus
Ergometrine, Terbutaline, Dinoprostone, Carboprost, Ritodrine, Oxytocin.
- Antimicrobial Drugs
- a) Sulfonamides
- b) Penicillins
- c) Cephalosporins
- d) Aminoglycosides
- e) Tetracyclines
- f) Macrolides
- g) Quinolones
- h) Anti-tuberculous drugs
- i) Antileprotic drugs
- j) Anti-fungal drugs
- k) Anti-viral drugs
- l) Anti-protozoal drugs
- Anti-malarial drugs
- Anti-amoebic drugs
- m) Urinary tract anti-septics
- n) Anti cancer drugs
- o) Immunosuppressive agents
- p) Miscellaneous
- q) Antihelmintics
- EXPERIMENTAL PHARMACOLOGY
Experiments on the actions of selected drugs to be demonstrated to students on suitable animal/tissue models.
- To study effects of drugs on rabbit’s eye
- To study effects of increasing dose of acetylcholine on isolated rabbit’s ileum.
- To study the effect of acetylcholine and atropine on isolated rabbit ileum
- To study effects of drugs on frog’s heart.
- To study the effect of neuromuscular blocking agent on frog rectus abdominal muscle
- To study introduction to biostatistics
- PHARMACY PRACTICLES
- Introduction to pharmacy equipment & their simpler implications
- Weights & measures/metrology, house-hold measure, temperature measuring system & their inter-conversions
- Introduction to various types of pharmacy/dosage forms and commonly used abbreviations in prescriptions
- To study pharmacognosy, crude drugs, active principals
- To prepare sulfur ointment
- To prepare KMNO4 lotion
- To prepare APC powders
- To prepare 5% glucose in normal saline and ORS
- To prepare carminative mixtures
- PRESCRIPTION WRITING
- Guideline for rationale use of drugs
- Prescription writing for common ailments:
- Drug concept
- Acute watery diarrhea
- Bacillary dysentery
- Amoebic dysentery
- Tape-worm infestation
- Acute streptococcal pharyngitis
- Iron deficiency anaemia
- Allergic rhinitis
- Acute malarial fever
- Cerebral malaria
- Typhoid fever
- Bronchial asthma
- Cardiac failure
- Clinicopharmacological Seminars on Rational Drug Therapy and Drug Interaction
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